Zhi Chen Selected Research

Dental Caries (Decay, Dental)

7/2010	Immunogenic characterization and protection against Streptococcus mutans infection induced by intranasal DNA prime-protein boost immunization.
11/2009	Enhanced immunogenicity of an anti-caries vaccine encoding a cell-surface protein antigen of Streptococcus mutans by intranasal DNA prime-protein boost immunization.
1/2007	A possible role of LIM mineralization protein 1 in tertiary dentinogenesis of dental caries treatment.
6/2006	Immunogenicity of CTLA4 fusion anti-caries DNA vaccine in rabbits and monkeys.
9/2005	Immunogenicity and protective efficacy of a targeted fusion DNA construct against dental caries.
6/2004	Mucosal immunization against dental caries with plasmid DNA encoding pac gene of Streptococcus mutans in rats.
5/2004	[Immunization with targeted fusion anticaries DNA vaccine via intramuscular route:experiment with murine].

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Zhi Chen Research Topics

Disease

125	Neoplasms (Cancer) 04/2022 - 01/2002
51	Inflammation (Inflammations) 12/2022 - 05/2004
50	Infections 09/2022 - 02/2002
36	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 11/2002
24	Fibrosis (Cirrhosis) 12/2021 - 01/2005
21	Chronic Hepatitis B 04/2021 - 01/2003
18	Hemorrhage 01/2021 - 02/2011
17	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2008
15	Liver Diseases (Liver Disease) 01/2022 - 02/2002
15	Cerebral Hemorrhage 01/2020 - 02/2011
14	Breast Neoplasms (Breast Cancer) 03/2022 - 10/2008
14	Brain Edema (Cerebral Edema) 01/2020 - 06/2014
13	Carcinogenesis 01/2022 - 04/2007
12	Brain Injuries (Brain Injury) 01/2020 - 09/2010
11	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 10/2011
10	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 11/2002
10	Hepatitis 01/2022 - 12/2005
10	Disease Progression 01/2021 - 08/2004
10	Hydrocephalus (Hydrocephaly) 01/2020 - 03/2014
10	Hepatitis B 01/2018 - 01/2005
9	Virus Diseases (Viral Diseases) 12/2022 - 01/2004
9	Myopia 02/2022 - 01/2016
9	Hematoma 11/2021 - 09/2014
8	Liver Neoplasms (Liver Cancer) 04/2022 - 03/2014
8	Hypoxia (Hypoxemia) 01/2022 - 12/2012
8	Osteosarcoma (Osteogenic Sarcoma) 06/2020 - 12/2012
8	Adenoma (Adenomas) 10/2017 - 10/2011
7	Necrosis 04/2022 - 09/2010
7	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 11/2015
7	Pneumonia (Pneumonitis) 02/2021 - 07/2008
7	Dental Caries (Decay, Dental) 07/2010 - 05/2004
6	Acute Liver Failure (Fulminant Hepatic Failure) 07/2022 - 10/2018
6	Rupture 06/2022 - 07/2008
6	Stomach Neoplasms (Stomach Cancer) 04/2022 - 01/2004
6	Acute Kidney Injury (Acute Renal Failure) 04/2022 - 11/2008
6	Polyps 01/2022 - 10/2011
6	Communicable Diseases (Infectious Diseases) 01/2022 - 06/2006
6	Alzheimer Disease (Alzheimer's Disease) 11/2021 - 08/2003
6	Mastitis 01/2021 - 10/2018
6	Neuroinflammatory Diseases 01/2021 - 11/2015
6	Persistent Infection 03/2014 - 11/2004
5	COVID-19 06/2022 - 01/2020
5	Traumatic Brain Injuries (Traumatic Brain Injury) 04/2022 - 06/2013
5	Obesity 12/2021 - 11/2012
5	Liver Failure 05/2021 - 02/2002
5	Spinal Cord Injuries (Spinal Cord Injury) 04/2021 - 11/2010
5	Parkinson Disease (Parkinson's Disease) 01/2021 - 12/2016
5	Leukemia 01/2021 - 07/2015
5	Hypersensitivity (Allergy) 11/2020 - 10/2003

Drug/Important Bio-Agent (IBA)

73	Proteins (Proteins, Gene)FDA Link 04/2022 - 03/2002
25	Biomarkers (Surrogate Marker)IBA 04/2022 - 03/2010
24	CytokinesIBA 01/2021 - 05/2004
22	MicroRNAs (MicroRNA)IBA 06/2021 - 05/2010
20	Pharmaceutical PreparationsIBA 06/2022 - 08/2004
20	Messenger RNA (mRNA)IBA 12/2021 - 11/2002
18	EnzymesIBA 01/2022 - 11/2005
15	Long Noncoding RNAIBA 04/2022 - 01/2011
14	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 01/2002
12	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 12/2013
12	AntigensIBA 04/2016 - 02/2002
10	VaccinesIBA 06/2022 - 07/2009
9	Glucose (Dextrose)FDA LinkGeneric 12/2022 - 10/2013
9	Antiviral Agents (Antivirals)IBA 12/2022 - 01/2005
9	Therapeutic UsesIBA 03/2022 - 01/2011
9	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2005
9	Phosphotransferases (Kinase)IBA 01/2022 - 12/2013
9	Hemoglobins (Hemoglobin)IBA 01/2022 - 10/2014
9	Interleukin-6 (Interleukin 6)IBA 01/2021 - 12/2002
9	LipopolysaccharidesIBA 01/2020 - 01/2014
7	AntibodiesIBA 06/2022 - 06/2004
7	LipidsIBA 05/2022 - 01/2017
7	InterleukinsIBA 01/2022 - 12/2002
7	InterferonsIBA 01/2021 - 12/2002
7	IronIBA 12/2018 - 04/2010
6	Oxygen (Dioxygen)IBA 05/2022 - 12/2012
6	Transcription Factors (Transcription Factor)IBA 12/2021 - 04/2006
6	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2021 - 02/2008
6	CalciumIBA 11/2021 - 11/2012
6	Interleukin-10 (Interleukin 10)IBA 01/2021 - 11/2007
6	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2016
6	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2020 - 07/2016
6	LigandsIBA 01/2020 - 07/2005
6	Hormones (Hormone)IBA 01/2020 - 02/2002
6	Concanavalin AIBA 05/2017 - 03/2010
6	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2016 - 01/2003
6	Estrogens (Estrogen)FDA Link 01/2016 - 09/2007
5	salicylhydroxamic acid (SHAM)IBA 01/2022 - 11/2010
5	CollagenIBA 12/2021 - 11/2002
5	Biological ProductsIBA 07/2021 - 04/2007
5	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2021 - 10/2012
5	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2021 - 10/2012

Therapy/Procedure

64	Therapeutics 02/2022 - 08/2003
19	Drug Therapy (Chemotherapy) 04/2022 - 01/2003
16	Immunotherapy 03/2022 - 11/2002
11	Length of Stay 05/2022 - 04/2014
11	Radiotherapy 01/2021 - 11/2005
8	Stents 07/2016 - 07/2008
7	Aftercare (After-Treatment) 03/2022 - 07/2008
6	Transplantation 01/2021 - 11/2010
5	Hematopoietic Stem Cell Transplantation 04/2022 - 02/2013